New monodisperse fully porous particles (MFPP) for HPLC

In this application note, Mac-Mod presents a new development in the silica particles used in particle size distribution (psd) of chromatographic materials, a less common discussion within high-performance liquid chromatography (HPLC). The note highlights how increased use of monodisperse stationary phases can improve monodispersity of silica particles, resulting in improved column efficiency amongst other numerous chromatographic parameters. The note also compares moving the chromatographic method from the laboratory to the production facility when using superficially porous particles (SPP), a more expensive method, to a more scalable method of production using monodisperse fully porous particles (MFPP) at affordable cost levels.