NGS Library Preparation Produces Balanced, Comprehensive Methylome Coverage from Low Input Quantities

Next-generation sequencing (NGS) of bisulfite-converted DNA to detect methylation status with per-base resolution is currently restricted by input requirements, requiring at least 50 ng of DNA. This Application Note shows how the unique chemistry of the Accel-NGS^® Methyl-Seq DNA Library Kit enables the construction of high complexity
libraries.