Novel bioassays in picodroplets: Accelerating biotherapeutics discovery and development

Many current technologies used in drug discovery and preclinical development programs typically involve multi-step operations, extensive hands-on time, and lengthy liquid handling processes as well as low-throughput bioassays for functional validation and verification. In this application note from Sphere Fluidics Ltd., explore how microfluidic devices, with well-defined microchannel geometries and accurate flow control, can be used to generate uniform picoliter volume droplets (picodroplets) for use as miniaturized “test tubes” for high-throughput bioassays.