Optical Measurements of Electrical Activity from hiPSC-Derived Cardiomyocytes is a Robust and High-Throughput Method for Measuring NCE-Effects on the Cardiac Action Potential

This poster presents data characterizing a novel optical platform, used in conjunction with Cellular Dynamics iCell® Cardiomyocytes, which offers a solution that overcomes the bottlenecks of low throughput and suitable tissue cells associated with traditional cardiac AP studies. This study investigates the effects of a range of pharmacological compounds on the cardiac AP, and demonstrates the suitability of these technologies for assessing NCE-mediated pro-arrhythmogenicity.