Overcoming challenges in LNP vector analysis: key tools, techniques, and considerations

In this application eBook, Malvern Panalytical highlights the potential of lipid-based nanoparticles (LNPs) for treating various medical conditions. LNPs efficiently deliver therapeutic RNA and can be rapidly scaled using cell-free production. However, LNPs' complex structure makes them analytically challenging to develop and manufacture. Key attributes like size, concentration, and thermal stability must be carefully controlled. Traditional techniques for established therapies are often insufficient for LNPs, necessitating complementary analytical tools. These tools aid in vector design, formulation development, and manufacturing, facilitating quicker delivery of improved medicines to patients.