Per- and Polyfluoroalkyl Substances (PFASs) in Drinking Water Using Solid-Phase Extraction and LC-MS/MS

This application note outlines a simple SPE procedure for the extraction of 26 diverse per- and polyfluoroalkyl substances (PFASs) in drinking water using UCT’s polymeric weak-anion exchange SPE cartridges (ENVIRO-CLEAN^® WAX). Instrumental analysis was carried out by LC-MS/MS in less than 10 minutes using a Selectra^® C18 HPLC column. Overall, excellent recovery and reproducibility were obtained at the low concentrations tested.