PhyTip® Columns Containing CaptureSelect® Resins for Purification of Antibodies and Antibody Fragments

In this application note the combination of PhyNexus separation columns and BAC resins is shown to provide an efficient and precise early stage evaluation for the spectrum of new developing antibody formats such as Fc fusions, Fab and FAb fragments, IgA’s, IgM’s, and IgG subclasses such as IgG4. Generating concentrated proteins from smaller volumes from more constructs earlier in the development process allows for additional analysis and subsequently better characterized biotherapeutics in the pipeline.