Polar Basic Drugs in Environmental Samples; Improved Analysis Using a New High Efficiency UPLC Column for HILIC

The purpose of this application note is to demonstrate the CORTECS UPLC HILIC Column for determination of highly polar basic compounds. In this application, a number of these compounds are determined in a spiked river water sample. Sample preparation was performed using the EPA 1694 method modified for use with a smaller sample volume and a smaller.