Precise MW Determination of Intact Proteins by Multiple Charge State Analysis of MALDI Generated Ions

This application note describes a new approach for the precise MW determination of intact protein proteins using multiple charge state analysis of MALDI generated ions. The combination of the new ultrafleXtreme with Bruker’s DHAP matrix provides very high accuracies for the MW determination of proteins in the 8-70 kDa range in a unique new concept of tracking advantage of highly resolved and multiple charged ions in a precisely calibrated m/z range.