Predictive High-Throughput Assays for Hepatotoxicity and Cardiac Physiology Using iPSC-Derived Cell Models

Development of highly predictive in vitro assays is extremely important for improving the drug development process and reducing drug attrition due to toxicity. iPSC-derived cell models are rapidly being adopted by the pharmaceutical industry for pre-clinical toxicity studies. iPSC-derived cells provide relevant human biology and are increasingly being shown to accurately predict drug-induced toxicity. In this poster, read about a physiological assay for measuring the impact of pharmacological compounds on the beating rate of human iPSC-derived cardiomyocytes.