Primary Epithelial Ovarian Cancer Cells form Spheroids when Cultured on Corning® Ultra-Low Attachment Surfaces

Epithelial ovarian cancer (EOC) does not follow a traditional metastatic route via the bloodstream; instead, its spread involves exfoliation of EOC cells from the primary tumor, aggregation into multicellular spheroids, and diffusion within the peritoneal cavity. This application note describes how Corning Ultra-Low Attachment tissue culture products are used for the generation of a model system that can recapitulate spheroids associated with EOC.