Protein concentration prediction in cell cultures

Biologically produced materials are an increasingly important aspect in many industrial processes including those related to pharmaceuticals, food, diagnostics, and fuels. Most of these biologicals are produced in fermenters and bioreactors in which specialized cell cultures grow and manufacture the molecule of interest. Monitoring and controlling cell culture conditions greatly reduces this variability and results in improved target protein production. In this application note from Thermo Fisher Scientific, explore how Fourier transform near-infrared (FT-NIR) spectroscopy has proven to be a useful technology for monitoring and controlling manufacturing processes including more specific bioprocess applications.