Protein extraction and purification for FFPE tissue

Formalin-fixed paraffin-embedded (FFPE) tissue samples are a valuable resource for studying the molecular mechanisms of disease and are widely used in genomics. Most sample preparation workflows for FFPE samples often result in highly degraded proteins with low yields, however Adaptive Focused Acoustics^® (AFA^®) Technology is the exception as it can be used for efficient extraction, purification, and expedited digestion of proteins from complex biological matrices, such as FFPE. Discover how Covaris developed a comprehensive workflow with Covaris technology for deparaffinization, extraction, purification, and digestion of proteins starting with just one 10 µm FFPE scroll.