Purification of Flavanone Glycoside with Reveleris® System Improves Polar Compound Isolation

This application note explains how using the Reveleris® system with RevealX™ technology and the high capacity Reveleris® amino cartridges, unreacted or even degraded reagents that may not be detected with UV detection can be isolated from a mixture of neohesperidin, hesperitin and neo-hesperidose during neohesperidin synthesis. Neohesperidin is an intensely bitter flavanone glycoside used for producing non-sugar sweetners for diabetes related therapy, naturally available from bitter orange.