Quantification of Antidepressants in Human Plasma or Serum by Liquid Chromatography-Tandem Mass Spectrometry

In this application note, an analytical method for clinical research for the quantification of 23 antidepressants in human plasma or serum is reported. The analysis includes:

atomoxetine, bupropion, citalopram, desmethylfluoxetine, desmethylmirtazapine, desmethylsertraline, dosulepin, duloxetine, threo-dihydrobupropion, fluoxetine, fluvoxamine, mianserin, milnacipran, mirtazapine, moclobemid, hydroxybupropion, opipramol, paroxetine, reboxetine, sertraline, tranylcypromine, trazodone, and venlafaxine.