Quantification of nitrosamines in water by automated PAL SPME-Arrow and GC/MS

Most nitroso compounds are suspected carcinogens in various animals including human beings. Human exposure to carcinogenic N-nitrosamines may result directly from ingestion or inhalation of preformed compounds from the environment. They are formed by the reaction of amines, especially secondary and tertiary amines or amino group containing compounds with nitrite (e.g. as food preservative). N-nitroso-dimethylamine (NDMA) and N-nitro so-diethylamine (NDEA) are the most common nitrosamines found in food materials. In this application note from CTC Analytics, explore a method for the quantitative analysis of a number of different N-nitrosamines from aqueous samples.