Quantitation of Opiates in Urine for Forensic Use Using an Affordable, High-Resolution, Accurate-Mass Mass Spectrometer

This application note presents a method for quantitation of six opiates—morphine, codeine, hydromorphone, hydrocodone, oxymorphone, and oxycodone—in human urine down to low ng/mL levels. This work was performed on a Q Exactive Focus hybrid quadrupole-Orbitrap mass spectrometer.