Quick and Sensitive Analysis of Multiclass Veterinary Drug Residues in Meat, Plasma, and Milk on a Q Exactive Focus LC-MS System

In this application note, the Q Exactive Focus MS in combination with an UltiMate 3000 HPLC was used to create a variable data-independent acquisition method for the detection and quantification of 44 multiclass veterinary drug residues. This novel method proved to have the required LOD sensitivity, and ability to confirm identity using retention time, accurate m/z, isotopic ratio, and fragment ions to exceed the EU regulatory requirements (EC/657/2002).