Rapid Fontana-Masson staining

The Fontana-Masson stain is used in the histological visualization of melanin and argentaffin (silver-binding) cells, found in tissue sections. The standard protocol, room temperature at 24°C, for this stain is 60 minutes for argentaffin or 30 minutes for melanin detection. In this study, MilliporeSigma evaluates a new rapid microwave protocol designed to be 30x faster than the standard.