Rapid peptide mapping and monitoring of post translational modifications using high resolution ion mobility mass spectrometry

In this application note, explore how MOBILion’s HRIM-MS platform can be used as a high throughput alternative to long LC-MS gradients by providing a rapid peptide mapping protocol.

Incorporating HRIM into an LC-MS workflow provided >96.5% sequence coverage in just 20 minutes total analysis time and included critical structural information that would have been missed using conventional LC-MS techniques alone.