Rapid Preparation of Released <i>N</i>-Glycans for HILIC Analysis Using a Novel Fluorescence and MS-Active Labeling Reagent

Conventional approaches to the preparation of N-glycans for HILIC-FLR-MS are either laborious, time-consuming, or require compromises in sensitivity. This application note describes a the development of the GlycoWorks RapiFluorFluor-MS N-Glycan Kit, designed to address the shortcomings described above by enabling unprecedented sensitivity for glycan detection while also improving the throughput of N-glycan sample preparation.