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Rapid, Sensitive, and Quantitative LC/MS/MS Determination of Digitoxin and Digoxin in Plasma

Using a Simple Procedure for Simultaneous Clean-up of Phospholipids and Proteins

18 Jan 2016

This application note describes the development of an LC/MS/MS method to measure digoxin and Digitoxin levels in the body, as these glycosides are used for treating heart conditions. Current methods using immunoassays are not selective between the two compounds due to the similarities between the molecules.

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