REAlease Fluorochrome Technology - Label-free Cells After Cell Sorting for Maximal Flexibility

REAlease^® Fluorochrome Technology relies on recombinantly engineered antibody fragments that are, unlike conventional antibodies, characterized by low epitope binding affinities. A novel covalent conjugation approach allows for multimerization and fluorescent labeling of these antibody fragments. They form the so called REAlease Fluorochrome Complex, which facilitates high-avidity cell binding that is comparable to conventional antibody fluorochrome conjugates. This novel and innovative conjugation chemistry allows for fast removal of the REAlease Fluorochrome Complex from the cell surface by adding the REAlease Release Reagent after flow sorting.