REDIchips™ for Rapid Quantitation of Low Molecular Weight Pharmaceutical Drugs Using Laser Desorption Ionization Mass Spectrometry

This poster investigates the performance of nanopost array devices (REDIchips) in quantitating small molecule pharmaceutical drugs in neat solutions and from biofluids. These nanoposts have dimensions matching the laser beam wavelength, and therefore couple laser light very effectively, resulting in electromagnetic field enhancement, high heating rates, and prolonged interaction times all of which promote desorption and ionization.