Reduction of Matrix-Induced Interferences for Transition Elements Using a Desolvating Nebulizer System with Quadrupole Inductively Coupled Plasma Mass Spectrometry

Matrix-based mass spectral interferences can compromise detection of a variety of transition elements when using quadrupole inductively coupled plasma mass spectrometry (ICP-MS). Cell-based quadrupole ICP-MS instruments can reduce such interferences using collision and/or reaction gases, but multi-element method development can be complex. This poster describes the use of a desolvating nebulizer system with quadrupole ICP-MS for reduction of the above listed interferences without use of cell gases. Installation steps and operating parameters for the desolvating nebulizer system will be detailed and figures of merit will include calibration, background equivalent concentrations (BECs), and instrument detection limits (IDLs).