Robustness characterization of a quantitative whole blood assay using PaperSpray technology for clinical research

This application note describes a method for quantitative and robust analysis of EDDP (2-ethylidene1,5-dimethyl-3,3-diphenylpyrrolidine), an opioid metabolite, in human whole blood for clinical research using the VeriSpray Paper Spray ion source coupled with a TSQ Quantis mass spectrometer.