Saliva preparation for rare tumor cell analysis workflow

17 Nov 2025

Detecting circulating tumor cells (CTCs) in head and neck squamous cell carcinoma (HNSCC) has long been a challenge. Low prevalence, diverse morphology, and reduced EpCAM expression all make detection difficult.

Together with Thomas Jefferson University, Bio-Rad has developed a streamlined liquid biopsy workflow using saliva to simplify rare tumor cell analysis.

Powered by the Genesis Cell Isolation System and Celselect Slides™ Technology, this new approach enriches and enumerates CTCs with greater efficiency. By using size-based selection, Bio-Rad helps overcome low yields and EpCAM variability, delivering clearer insights for cancer research.

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