Screening of 300 Drugs in Blood Utilizing Second Generation Exactive Plus High-Resolution, Accurate Mass Spectrometer and ExactFinder Software

This scientific poster describes the evaluation of Thermo Scientific Exactive Plus high performance bench-top mass spectrometer for drug screening of whole blood for forensic toxicology purposes. Whole blood samples were processed by precipitation with ZnSO₄/methanol. Samples were injected onto a HPLC under gradient conditions and detected on a Exactive^TM Plus Mass Spectrometer. Results were analyzed with Thermo Scientific ExactFinder software.