SEC-MALS for absolute biophysical characterization

In this whitepaper, Waters | Wyatt Technology outline the importance of accurate biomacromolecule characterization for successful research and development in life sciences and biopharmaceuticals. The fundamental biophysical properties, including molecular weight, size, conformation, degree of conjugation, aggregation, and complex-forming interactions, are crucial considerations. The paper delves into the technology, capabilities, and applications of light scattering paired with size-exclusion chromatography for biophysical characterization.