Sensitive Detection of Peptides in Cytochrome C Digest Using Nano LC

Liquid chromatography coupled with mass spectrometry is a powerful analytical tool for detection and identification of chemicals in complex mixtures. With the low flow capability of Nano LC-MS, higher resolution, ion suppression tolerance and ionisation efficiency is obtained which gives greater chemical sensitivity. The low flow capability of nano-LC couples perfectly with the microfluidics of the Microsaic 4500 MiD^® mass detector. The reduced solvent, nitrogen and power consumption of the Microsaic 4500 MiD^® provides a lower cost and greener solution for mass detection.