Sensitive protein quantification in crude serum samples: Comparison of FO-SPR and ELISA

This application note demonstrates the potential of FOx BIOSYSTEMS’ fiber-optic surface plasmon resonance technology (FO-SPR) for determining the concentration of a protein or antibody in crude samples, like serum. As an example, FOx demonstrate the detection of the therapeutic monoclonal antibody, infliximab (IFX), in patient serum samples. FO-SPR is a powerful tool that harnesses the power of SPR in an easy-to-use fiber-optic sensor.