Setup of a Microbial Hyaluronic Acid Production Process Using the BioFlo® 120 Bioprocess Control Station

Achieving optimal process conditions for microbial growth and production of a desired bioproduct needs hardware and software to monitor and control the bioprocess parameters, including the pH, temperature, and agitation of the fermentation broth. Researchers at Praj Industries, India used the BioFlo 120 bioprocess control station to produce hyaluronic acid (HA) in Streptococcus zooepidemicus at bench scale. In this application note they describe how they set up, monitored, and controlled critical process parameters, and thus present an impression of the controller’s integrated, touch screen accessible software.