Simultaneous analysis of 19 novel synthetic cannabinoids in urine using SPE and LC-MS/MS

This application note outlines a solid-phase extraction (SPE) and LC-MS/MS method for the analysis of 19 synthetic cannabinoids in urine. These specific compounds were selected based on positivity rates from several key testing labs in the area. The use of UCT’s Styre Screen® HLD highly crosslinked polymeric SPE sorbent ensures efficient extraction of the synthetic cannabinoids while removing undesired matrix components and yielding clean extracts