Solid Phase Extraction Method Development for Bioanalytical Therapeutic Peptides

This technical note explores how a peptide screening method can be used with a specialized method development plate (Strata-X peptide screening microelution plate) containing a polymeric strong anion-exchange (Strata-X-A) and a polymeric weak cation-exchange phase (Strata-X-CW), to determine which one is the most appropriate choice for a wide range of chemically diverse peptides.