Solid Phase Extraction Method for Analysis of Psilocin and Psilocybin in Urine

This application note describes a method that can be used for the extraction of Psilocin and Psilocybin in urine. LC/MS/MS instrumentation is used for analysis with a linear range of 10 ng/mL to 1000 ng/mL with average recoveries of individual cannabinoids found to be greater than 85%.