Solid Phase Extraction of US EPA 535 for Herbicide Degradates in Drinking Water Samples

In this application note, determination of chloroacetanilide and acetamide degradates was performed using the automated SmartPrep® Extractor SPE cartridge system according to US EPA 535 prior to LC/MS/MS analysis, with the intent to generate results within the acceptance criteria of the EPA 535 method. The US EPA has implemented an exposure research program aimed at conducting drinking water research on methods as part of the Microbiological and Chemical Exposure Assessment. This research is aimed at evaluating the chemical pollutants and their role and levels in which there is an unacceptable risk to humans or wildlife, as well as evaluating the methodologies currently being used to determine levels of chemical pollutants.