Stem Cell Research: Creating Blood for High Throughput Screening

Many different research fields – including investigation of early human development processes, disease research, drug discovery and cellular therapy applications – require appropriate in vitro models which can accurately mimic in vivo processes to provide biologically relevant results. Pluripotent stem cells (PSCs) offer a powerful system for creating in vitro models to address these questions. This study describes a highly efficient, serum-free, feeder-free automated system for production of iPSCs, and their differentiation into hematopoietic precursor cells (HPCs).