Streamline Assessment of DNA Damage Using the ImageXpress Nano System

Assessing damage to DNA or chromosomes is frequently addressed with research applications because of its implications in diverse diseases including genetic mutations, cancer, and aging. DNA damage may occur spontaneously or result from exposure to ionizing radiation, environmental influences and contaminants, or chemical compounds. Previous research demonstrated that phosphorylation of histone H2AX on serine139 is an early and sensitive indicator of DNA double-strand breaks.