Subvisible particles – Why don’t I just filter my biologic samples?

Filtration of a therapeutic is often cited as a key method to remove particles generated during the manufacturing process. While filtration removes preformed particles, including subvisible particles (SVPs), it does not account for the inherent instability of biologic samples, and thus subvisible aggregates can be generated over time even after filtration.

Explore how Aura^® and Backgrounded Membrane Imaging (BMI) was used to explore the effect of filtration on three different biologic formulations. Plus, discover how Aura was able to provide a rapid long-term stability assessment via a low volume, high-throughput assay.