Targeted MRM screening of U-13C lipid yeast extracts for robust lipidomics applications

Fatty acids (FAs) and lipids are important biological compounds that are essential to the regulation and control of cellular functions (e.g., membrane structure, signal transduction, apoptosis) and metabolic pathways (e.g., fatty acid oxidation, ketone body synthesis, lipolysis). These biomolecules are also functionally important to an organism’s energy production and storage.

In this application note, Cambridge Isotope Laboratories qualifies a condensed panel of stable isotope-labeled FAs/lipids in U-13C crude lipid yeast extracts on robust, high-throughput, analytical platforms.