Targeted Screening of 130 Pesticides in QuEChERS Extracts of Lettuce Leaves Using UHPLC-TOF and High Throughput Screening Software

This application note describes the analysis of 130 pesticides in a lettuce leaves extract obtained by the QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) method of food extraction. Ultra-High Pressure Liquid Chromatography-Mass Spectrometry (UHPLC-MS) analysis was performed with a PerkinElmer AxION® 2 TOF MS as the detector. A majority of pesticides were detected within the EU limit of detection (LOD) requirement range of 10 ppb. The data was further analyzed using AxION Solo™ high throughput software.