Effectiveness of the AC extraction plate for protein removal

When determining small molecules in biological matrices by liquid chromatography mass spectrometry (LC/MS), it is important to ensure that the sample preparation steps remove any interfering matrix components prior to sample injection. Common procedures to remove proteins can be complex and time consuming. Explore how simple procedures can be applied with the Tecan AC Extraction Plate to remove proteins from a sample matrix, and that the protein is not retained in the TICE™ coating covering the lower part of the plate’s wells.