The Advantages of the NexION 300D ICP-MS for the Determination of Titanium in Serum

The PerkinElmer NexION® 300D ICP-MS is a robust, highly innovative cell-based system benefitting from three quadrupoles with the middle one acting as a universal cell. This cell can be used both as a collision cell using inert gases, such as He, and as a true dynamic reaction cell with the benefits of using the most appropriate reactive gas for the efficient targeting of any spectral interference. This application note describes a method to shift the Ti ions away from the interferences using Reaction mode with ammonia as the reaction gas to determine the concentration of Ti in serum.