The Analysis of Dermorphin, an Opioid Peptide in Equine Plasma using the EVOQ Elite

This application note demonstrates the quantification of demorphin, a naturally occurring hepta-peptide and class I prohibited substance in horse racing, in equine plasma using solid phase extraction cleanup. Due to the associated complex matrix and lack of a stable labeled internal standard, the analysis of dermorphin in equine plasma is a challenging assay, but was easily achieved on the EVOQ Elite LC-TQ.