The Role of Tyrosine Kinases in Cancer and Drug Research

This white paper describes how Luminex xMAP Technology has been used to develop multiplex assays to advance the understanding of tyrosine kinase activity in several types of cancer, including glioblastoma, thyroid cancer, pediatric cancer, and lung cancer. It also covers novel ways that multiplex technology is being used in the study of tyrosine kinase related cancer drug therapy, through genetic testing of somatic mutations in the study of TKI response, and through the development of tyrosine kinase activity screens for drug discovery.