The YMC-Accura Triart Bio C4 column for AAV capsid protein analysis

27 May 2024

Traditional methods such as ELISA and SDS-PAGE are labor-intensive and imprecise, whereas reversed phase liquid chromatography (RP-LC) coupled with mass spectrometry (MS) offers better accuracy for quantifying viral proteins VP1, VP2, and VP3. YMC Europe presents the YMC-Accura Triart Bio C4 column as the optimal choice for analyzing adeno-associated virus (AAV) capsid proteins, which are crucial for gene therapy applications. Further, YMC Europe highlights a study that compares the bioinert YMC-Accura Triart Bio C4 column to standard columns, demonstrating that the bioinert coating significantly improves resolution, peak shape, and retention times by preventing protein adsorption to the column hardware.

Links

Tags