Three-dimensional Culture and Assessment of Drug-Induced Cell Death Using the CellASIC^® ONIX Microfluidic Platform

This application note uses the CellASIC^® ONIX Microfluidic System, in conjunction with the M04S microfluidic plate, to achieve perfusion-based microenvironment control and study drug-induced cell death of 3D cultures of MCF7 cells in Matrigel^®. The microfluidic chamber recreates the physiologic mass transport condition for optimized cell health.