Through-Container Identity Verification of Polysorbates with the Agilent RapID Raman System

Polysorbates are often packaged in a sealed, oxygen-free environment to prevent degradation. Amber glass bottles are common containers for polysorbates, often used in large numbers, making identification difficult and time-consuming. Manufacturers of polysorbates typically make different grades, so reliable identity verification is essential to mitigate mistakes in supply. This Application Note describes how the Agilent RapID Raman system can unambiguously verify the identity of the four common pharmaceutical grades of polysorbates through unopened amber glass bottles.