Titanium Dioxide Nanoparticle Dispersions in Cell Culture Media Characterized by High-Throughput DLS

Characterization of nanoparticle size and distribution in biological environments and understanding the parameters that affect them are imperative to accurately assess nanoparticle toxicity. This application note describes a study in which TiO₂ nanoparticle size is determined using the DynaPro™ Dynamic Light Scattering Detector by Wyatt Technology Corp. The study demonstrates that this method is a convenient and effective tool and for evaluating the effects of different dispersing agents much faster than conventional “batch” DLS.