Transfer of the HPLC Method for Related Substances Analysis of Metoclopramide HCl from an Agilent 1260 Infinity LC System to an ACQUITY Arc System

Analysis of an active pharmaceutical ingredient and its related substances must be conducted by every manufacturer to ensure the safety and efficacy of the end product. Often, these assays are performed across the organization or in partner laboratories so consistent and effective method transfer is crucial. This application note demonstrates the transfer of the HPLC method for related substances analysis of metoclopramide HCl from an Agilent 1260 Infinity LC System to an ACQUITY Arc System.